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Internal Guardians: Three Core Functions of the Immune System and Allergic Reactions
SCI901B-SEP-CNLesson 4
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Imagine your body as a bustling modern city,immune systemis the collective force of the city's Public Security Bureau, Sanitation Department, and National Security Agency. It is not merely a simple antivirus program, but an extremely sophisticatedmolecular recognition and response mechanism. The immune system maintains the balance and dignity of our life activities by distinguishing between 'self' (Self) and 'non-self' (Non-self).

DefenseHomeostasisSurveillanceHyperactivity โ†’ Allergy

Core Functional Analysis

  • Defense Function (External): Like troops stationed at the border, it blocks and eliminates invading pathogens. If this military force is overly 'sensitive' or 'impulsive', attacking harmless substances like pollen or drugs, it can triggerallergic reactions.
  • Homeostasis (Internal): Equivalent to the city's sanitation workers. It identifies and clears out aged, dead, or damaged cells that have exceeded their service life, maintaining internal environmental cleanliness.
  • Immune Surveillance (Counterintelligence): Like a round-the-clock surveillance system. It detects and eliminates occasional 'traitors'โ€”abnormal cells (such as tumor cells)โ€”within the body. If this system fails, abnormal cells proliferate unchecked, leading to tumor development.
The Essence of Allergies
When the defense function becomeshyperactivedue to genetic or environmental factors, the immune system treats 'ordinary people' as enemies, triggering a strong antigen-antibody reaction. Mast cells release histamine, causing capillary dilation, manifesting as rashes, sneezing, or even fatal shock. This is also a cost of the immune system's flawed 'recognition logic'.